Duplex High-Resolution Melting Assay for the Simultaneous Genotyping of IL28B rs12979860 and PNPLA3 rs738409 Polymorphisms in Chronic Hepatitis C Patients.

doi:10.3390/ijms160922223

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Duplex High-Resolution Melting Assay for the Simultaneous Genotyping of IL28B rs12979860 and PNPLA3 rs738409 Polymorphisms in Chronic Hepatitis C Patients.

International journal of molecular sciences - 14 Sept 2015

Enache Elena L, Sin Anca, Bancu Ligia, Ramière Christophe, Diaz Olivier, André Patrice, Enache Liviu S

Abstract excerpt

Chronic hepatitis C (CHC) is a major burden for public health worldwide. Although newer direct-acting antivirals show good efficacy, their cost precludes their wide adoption in resource-limited regions. Thus, strategies are being developed to help identify patients with high susceptibility to response to classic PEG-interferon + ribavirin therapy. IL28B polymorphism rs12979860 C/T is an important predictor for an...

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PMID: 26389885
DOI: 10.3390/ijms160922223
PMCID: PMC4613305

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PNPLA3

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