Article

Diagnostic and Therapeutic Microbial Circuit with Application to Intestinal Inflammation

2020-11-10

Abstract excerpt

Bacteria genetically engineered to execute defined therapeutic and diagnostic functions in physiological settings can be applied to colonize the human microbiome, providing in situ surveillance and conditional disease modulation. However, many engineered microbes can only respond to single-input environmental factors, limiting their tunability, precision, and effectiveness as living diagnostic and therapeutic sys...

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Literature Corpus work: 718b5a0e-f26d-50e9-9213-45370f183068
DOI: 10.1101/2020.11.10.377085

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