Article

Thermo-amplifier circuit in probiotic <i>E. coli</i> for stringently temperature-controlled release of a novel antibiotic

2024-02-15

Abstract excerpt

Peptide drugs have seen rapid advancement in biopharmaceutical development, with over 80 candidates approved globally. Despite their therapeutic potential, the clinical translation of peptide drugs is hampered by challenges in production yields and stability. Engineered bacterial therapeutics is a unique approach being explored to overcome these issues by using bacteria to produce and deliver therapeutic compounds...

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Literature Corpus work: b65fe628-db0e-5b64-abd4-8a671c1fb880
DOI: 10.1101/2024.02.13.579303

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