Article

A discovery platform to identify inducible synthetic circuitry from varied microbial sources

2023-10-13

Abstract excerpt

Gut microbes encode a variety of systems for molecular sensing and controlling conditional gene expression within the mammalian gut. Synthetic biology approaches such as whole-cell biosensing and 'sense-and-respond' therapeutics aim to tap into this vast sensing repertoire to drive clinical and pre-clinical applications. An ongoing constraint is the limited number of well-characterized inducible circuit components...

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Literature Corpus work: 56521730-4e20-5c35-a723-5bb50e36526c
DOI: 10.1101/2023.10.13.562223

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