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Synthetic bacterial therapies for intestinal diseases based on quorum-sensing circuits

26 Mar 2023

Abstract excerpt

Bacterial therapy has become a key strategy against intestinal infectious diseases in recent years. Moreover, regulating the gut microbiota through traditional fecal microbiota transplantation and supplementation of probiotics faces controllability, efficacy, and safety challenges. The infiltration and emergence of synthetic biology and microbiome provide an operational and safe treatment platform for live...

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PMID: 36977440
DOI: 10.1016/j.biotechadv.2023.108142

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