Article

Plakoglobin is a mechanoresponsive regulator of naïve pluripotency

2022-03-16

Abstract excerpt

Biomechanical cues are instrumental in guiding embryonic development and cell differentiation. Understanding how these physical stimuli translate into transcriptional programs could provide insight into mechanisms underlying mammalian pre-implantation development. Here, we explore this by exerting microenvironmental control over mouse embryonic stem cells (ESCs). Microfluidic encapsulation of ESCs in agarose micro...

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Literature Corpus work: 715e7ab1-f4ed-5d3e-8248-d674e5e43044
DOI: 10.1101/2022.03.13.484158

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