Article

Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling

2019-10-04

Abstract excerpt

Cell replacement therapies hold great therapeutic potential. Nevertheless, our knowledge of the mechanisms governing the developmental processes is limited, impeding the quality of differentiation protocols. Generating insulin-expressing cells in vitro is no exception, with the guided series of differentiation events producing heterogeneous cell populations that display mixed pancreatic islet phenotypes and immat...

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Literature Corpus work: 7635241d-4147-5b78-b839-9deaba9fc607
DOI: 10.1101/791442

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