Article

Investigating the role of opiorphin genes in prostate cancer and the possible genetic mechanisms by which they modulate tumor growth and androgen-sensitivity.

2020-09-28

Abstract excerpt

<title>Abstract</title> <bold>Background </bold>The opiorphin family of genes (represented in humans by <italic>ProL1,</italic> <italic>hSMR3A and hSMR3B)</italic> encode peptides which act as potent neutral endopeptidase (NEP) inhibitors. Because modulated NEP activity is associated with cancer development it has been suggested that dysregulated opiorphin expression may be involved in oncogenesis and recent r...

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Literature Corpus work: 71218960-3c43-5ebd-90c9-89c686205072
DOI: 10.21203/rs.3.rs-30262/v2

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