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EXPRESSION PROFILE OF AN ANDROGEN REGULATED PROSTATE SPECIFIC HOMEOBOX GENE <i>NKX3.1</i> IN PRIMARY PROSTATE CANCER

1 Mar 2000

Abstract excerpt

PURPOSE: NKX3.1, a member of the family of homeobox genes, exhibits prostate tissue specific expression and appears to play a role in mouse prostate development. Rapid induction of NKX3.1 gene expression in response to androgens has also been described. On the basis of the established role of androgens in prostatic growth and differentiation and studies showing an association of aberrant homeobox gene expression...

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PMID: 10688034
DOI: 10.1016/s0022-5347(05)67867-6

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