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Article

The opiorphin gene (ProL1) and its homologues function in erectile physiology

11 Apr 2008

Abstract excerpt

OBJECTIVE: To determine if ProL1, a member of the opiorphin family of genes, can modulate erectile physiology, as it encodes a peptide which acts as a neutral endopeptidase inhibitor, other examples of which (Vcsa1, hSMR3A) modulate erectile physiology. MATERIALS AND METHODS: We cloned members of the opiorphin family of genes into the same mammalian expression backbone (pVAX); 100 microg of these plasmids...

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PMID: 18410445
DOI: 10.1111/j.1464-410x.2008.07631.x

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