Article

SjDX5-271 Promotes M2 Microglia/Macrophage Polarization to Enhance Retinal Pigment Epithelium Transplantation Efficacy

2026-08-06

Abstract excerpt

<title>Abstract</title> <p>Age-related macular degeneration (AMD) causes irreversible vision loss via progressive degeneration of the retinal pigment epithelium (RPE) and photoreceptors. RPE transplantation is a promising therapeutic approach for retinal degeneration, yet immune-mediated graft rejection severely impairs its clinical efficacy. Microglia/macrophage M1/M2 polarization dominates the post-transplantat...

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Literature Corpus work: 70db0965-f6d9-532b-bc00-4fb789dff218
DOI: 10.21203/rs.3.rs-10422989/v1

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