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Sialic Acid Mimetic Microglial SIGLEC Agonistic Nanoparticle: Potential to Restore Retinal Homeostasis and Regain Visual Function in AMD

2023-10-18

Abstract excerpt

Age-related macular degeneration, a leading cause of visual loss and dysfunction in the devel-oped world, is a disease initiated by genetic polymorphisms that impairs negative regulation of complement. Proteomic investigation points to altered glycosylation and loss of SIGLEC medi-ated glyco-immune checkpoint parainflammatory homeostasis as a main determinant for the vi-sion impairing complications of macular dege...

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Literature Corpus work
d9efca93-1535-5a9c-9712-435ea1c41148
DOI
10.20944/preprints202310.1159.v1
Open publication

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Sialic Acid Mimetic Microglial SIGLEC Agonistic Nanoparticle: Potential to Restore Retinal Homeostasis and Regain Visual Function in AMDDOI 10.20944/preprints202310.1159.v1
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