Article

Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions

2023-07-19

Abstract excerpt

Degenerative diseases of the outer retina, including age-related macular degeneration (AMD), are characterized by atrophy of photoreceptors and retinal pigment epithelium (RPE). In these blinding diseases, macrophages are known to accumulate ectopically at sites of atrophy, but their ontogeny and functional specialization within this atrophic niche remain poorly understood, especially in the human context. Here, w...

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Literature Corpus work: a5d8b465-3f59-53b1-8ebd-1975cac33fad
DOI: 10.1101/2023.07.19.549403

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Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 InteractionsDOI 10.1101/2023.07.19.549403Read

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