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Advances in DNA damage response inhibitors in colorectal cancer therapy

4 Dec 2023

Abstract excerpt

One potential cause of cancer is genomic instability that arises in normal cells due to years of DNA damage in the body. The clinical application of radiotherapy and cytotoxic drugs to treat cancer is based on the principle of damaging the DNA of cancer cells. However, the benefits of these treatments also have negative effects on normal tissue. While there have been notable advancements in molecular-driven...

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PMID: 38115743
DOI: 10.3724/abbs.2023278

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