Article

<i>In silico</i> study predicts a key role of RNA-binding domains 3 and 4 in nucleolin-miRNA interactions

2021-06-10

Abstract excerpt

RNA binding proteins (RBPs) regulate many important cellular processes through their interactions with RNA molecules. RBPs are critical for post-transcriptional mechanisms keeping gene regulation in a fine equilibrium. Conversely, dysregulation of RBPs and RNA metabolism pathways is an established hallmark of tumorigenesis. Human nucleolin (NCL) is a multifunctional RBP that interacts with different types of RNA m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f71d1890-3ddc-5e43-9d4f-ddb4412a48b2
DOI: 10.1101/2021.06.09.447752

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>In silico</i> study predicts a key role of RNA-binding domains 3 and 4 in nucleolin-miRNA interactionsDOI 10.1101/2021.06.09.447752Read

In silico study predicts a key role of RNA-binding domains 3 and 4 in nucleolin-miRNA interactions.Semantic proximity Read

A Survey of Current Resources to Study lncRNA-protein Interactions.Semantic proximity Read

The hnRNP family: insights into their role in health and diseaseSemantic proximity Read

Drugs targeting microRNAs that regulate DNA damage sensing and repair mechanisms: <i>A computational drug discovery approach</i>Semantic proximity Read

Fully Complementary Interactions of LmiRNA with mRNA of Human GenesSemantic proximity Read

EuRBPDB: a comprehensive resource for annotation, functional and oncological investigation of eukaryotic RNA binding proteins (RBPs)Semantic proximity Read

RNA-Binding Motif Protein 3 as a Therapeutic and Prognostic Target for Drug DiscoverySemantic proximity Read

Discovery of a Well-Folded Protein Interaction Hub Within the Human Long Non-Coding RNA <i>NORAD</i>Semantic proximity Read

RNA recognition motif of LEMD3 as a key player in the pathogenesis of Buschke-Ollendorff syndrome.Semantic proximity Read

Human Pumilio proteins use fuzzy multivalent hydrophobic interactions to recruit the CCR4–NOT deadenylase complex to repress mRNAsSemantic proximity Read

High-throughput discovery of regulatory effector domains in human RNA-binding proteinsSemantic proximity Read

Comprehensive Identification of RNA-Binding Domains in Human Cells.Semantic proximity Read