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Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

27 Sept 2023

Abstract excerpt

Influenza A Virus (IAV) is a recurring respiratory virus with limited availability of antiviral therapies. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry and global phosphoproteomic and protein abundance analyses using three IAV strains (pH1N1, H3N2, H5N1) in three human cell types (A549,...

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PMID: 37758692
DOI: 10.1038/s41467-023-41442-z

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