Article
Phosphoproteomic analyses reveal signaling pathways that facilitate lytic gammaherpesvirus replication.
PLoS pathogens - 1 Sept 2013
Stahl James A, Chavan Shweta S, Sifford Jeffrey M, MacLeod Veronica, Voth Daniel E, Edmondson Ricky D, Forrest J Craig
Abstract excerpt
Lytic gammaherpesvirus (GHV) replication facilitates the establishment of lifelong latent infection, which places the infected host at risk for numerous cancers. As obligate intracellular parasites, GHVs must control and usurp cellular signaling pathways in order to successfully replicate, disseminate to stable latency reservoirs in the host, and prevent immune-mediated clearance. To facilitate a systems-level...
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