The comprehensive SARS-CoV-2 ‘hijackome’ knowledge base— reveals significant changes in host cell protein expression and activation by multiple SARS-CoV-2 variants

Abstract excerpt

<title>Abstract</title> <p>The continuous evolution of SARS-CoV-2 has led to the emergence of several variants of concern (VOCs) that significantly affect global health. This study aims to investigate how these VOCs affect host cells at proteome level to better understand the mechanisms of disease. To achieve this, we first analyzed the (phospho)proteome changes of host cells infected with Alpha, Beta, Delta, and...

Topics

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• COVID-19 Clinical Research Studies
• Influenza Virus Research Studies
• interferon and immune responses
• SARS-CoV-2 and COVID-19 Research
• SARS-CoV-2 detection and testing

Identifiers and source

Literature Corpus work

2822d042-93cc-5746-aac6-e6061cdfdbc4

DOI

10.21203/rs.3.rs-4322477/v1