Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel Host Proteins and Signaling Pathways in Enteropathogenic E. coli Pathogenesis Identified by Global Phosphoproteome Analysis *

5 May 2015

Abstract excerpt

Enteropathogenic Escherichia coli (EPEC) uses a type III secretion system (T3SS) to directly translocate effector proteins into host cells where they play a pivotal role in subverting host cell signaling needed for disease. However, our knowledge of how EPEC affects host protein phosphorylation is limited to a few individual protein studies. We employed a quantitative proteomics approach to globally map...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Genetics and Biotechnology
Share to Escherichia coli research studies
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25944883
DOI: 10.1074/mcp.m114.046847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel Host Proteins and Signaling Pathways in Enteropathogenic E. coli Pathogenesis Identified by Global Phosphoproteome Analysis *PMID 25944883Read ↗

Cell type-independent profiling of interactions between intracellular pathogens and the human phosphoproteomeSemantic proximity Read ↗

Addressing the effects of Salmonella internalization in host cell signaling on a reverse-phase protein array.Semantic proximity Read ↗

Characterization of TccP-mediated N-WASP activation during enterohaemorrhagic Escherichia coli infection.Semantic proximity Read ↗

EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly.Semantic proximity Read ↗

Phosphorylation of CFP10 modulates Mycobacterium tuberculosis virulenceSemantic proximity Read ↗

A diarrheal pathogen, enteropathogenic Escherichia coli (EPEC), triggers a flux of inositol phosphates in infected epithelial cells.Semantic proximity Read ↗

EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPasesSemantic proximity Read ↗

In-Depth Characterization of the Staphylococcus aureus Phosphoproteome Reveals New Targets of Stk1Semantic proximity Read ↗

SepZ/EspZ Is Secreted and Translocated into HeLa Cells by the Enteropathogenic Escherichia coli Type III Secretion SystemSemantic proximity Read ↗

Cytokeratin 18 interacts with the enteropathogenic Escherichia coli secreted protein F (EspF) and is redistributed after infectionSemantic proximity Read ↗

Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation.Semantic proximity Read ↗

Enterohaemorrhagic Escherichia coli Tir requires a C-terminal 12-residue peptide to initiate EspF-mediated actin assembly and harbours N-terminal sequences that influence pedestal length.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.