Article

Modulation of human kinase activity through direct interaction with SARS-CoV-2 proteins

2023-11-27

Abstract excerpt

The dysregulation of cellular signaling upon SARS-CoV-2 infection is mediated via direct protein interactions, with the human protein kinases constituting the major impact nodes in the signaling networks. Here, we employed a targeted yeast two-hybrid matrix approach to identify direct SARS-CoV-2 protein interactions with an extensive set of human kinases. We discovered 51 interactions involving 14 SARS-CoV-2 prote...

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Literature Corpus work: 9de1752f-19c5-5895-a171-d19e2d882a00
DOI: 10.1101/2023.11.27.568816

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