Article

Cross-Disorder Machine Learning Uncovers Schizophrenia Risk Variants Predictive of Alzheimer’s Disease

2025-04-25

Abstract excerpt

Alzheimer’s disease (AD) and Schizophrenia (SCZ) exhibit overlapping clinical features and biological mechanisms, but the extent of their shared genetic etiology and the potential for cross-disorder risk prediction are not fully elucidated, with previous genetic studies yielding mixed results. This study investigated whether integrating statistically-selected SCZ-associated single nucleotide polymorphisms (SNPs),...

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Literature Corpus work: 70bf6339-b8be-5d95-bad5-57e433da1ebf
DOI: 10.1101/2025.04.24.25326362

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