Article

Shared genetic background between cerebrospinal fluid biomarkers and risk for Alzheimer’s disease: A two-sample Mendelian randomisation study

2020-03-17

Abstract excerpt

<title>Abstract</title> <p>Background: Whether the epidemiological association of amyloid beta (Aβ) and tau pathology with Alzheimer’s disease (AD) is causal remains unclear. Recent failures to demonstrate the efficacy of several Aβ-modifying drugs may indicate a possibility that the observed association is not causal, which led to efforts to develop tau-directed treatments whose efficacy remains tentative. <h4>M...

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Literature Corpus work: 709a5d38-c08b-550b-9d23-462057503bfb
DOI: 10.21203/rs.3.rs-17511/v1

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