Article
Amyloid, tau and risk of Alzheimer's disease: a Mendelian randomization study.
European journal of epidemiology - 1 Jan 2021
Yeung Chris Ho Ching, Lau Kathleen Wen Din, Au Yeung Shiu Lun, Schooling C Mary
Abstract excerpt
This study was carried out to assess the effect of amyloid and tau on Alzheimer's disease using two-sample Mendelian randomization design. Genetic associations with plasma amyloid species (amyloid precursor protein, amyloid-like protein 2, serum amyloid P-component, amyloid beta peptide), cerebrospinal fluid (CSF) amyloid beta, total tau, and phosphorylated tau181 were extracted from the largest genome-wide...
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