Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic architecture of plasma Alzheimer disease biomarkers

19 May 2023

Abstract excerpt

Genome-wide association studies (GWAS) of cerebrospinal fluid (CSF) Alzheimer's Disease (AD) biomarker levels have identified novel genes implicated in disease risk, onset and progression. However, lumbar punctures have limited availability and may be perceived as invasive. Blood collection is readily available and well accepted, but it is not clear whether plasma biomarkers will be informative for genetic...

Topics

Join the communities discussing this publication.

Alzheimer's disease research and treatments
Bioinformatics and Genomic Networks
S100 Proteins and Annexins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37208024
DOI: 10.1093/hmg/ddad087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic architecture of plasma Alzheimer disease biomarkersPMID 37208024Read ↗

Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer’s diseaseSemantic proximity Read ↗

Genetic architecture of Alzheimer’s disease-related plasma biomarkersSemantic proximity Read ↗

Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach.Semantic proximity Read ↗

Shared genetic background between cerebrospinal fluid biomarkers and risk for Alzheimer’s disease: A two-sample Mendelian randomisation studySemantic proximity Read ↗

Polygenic Scores of Core-1 Alzheimer’s Disease Biomarkers Predict Early Cognitive and Pathological ChangeSemantic proximity Read ↗

Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer’s Disease related proteinsSemantic proximity Read ↗

Shared Genetic Background Between Cerebrospinal Fluid Biomarkers and Risk for Alzheimer's Disease: A Two-Sample Mendelian Randomization Study.Semantic proximity Read ↗

An Integrated Bioinformatics Approach for Identifying Genetic Markers that Predict Cerebrospinal Fluid Biomarker p-tau181/Aβ1-42 Ratio in ApoE4-Negative Mild Cognitive Impairment Patients.Semantic proximity Read ↗

Heritability of Alzheimer's disease plasma biomarkers: A nuclear twin family designSemantic proximity Read ↗

Alzheimer's Disease polygenic risk, the plasma proteome, and dementia incidence among UK older adults.Semantic proximity Read ↗

Degree of genetic liability for Alzheimer's disease associated with specific proteomic profiles in cerebrospinal fluid.Semantic proximity Read ↗

Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.