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Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of<i>cis</i>-regulation

2024-11-15

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWAS) of melanoma risk have identified 68 independent signals at 54 loci. For most loci, specific functional variants and their respective target genes remain to be established. Capture-HiC is an assay that links fine-mapped risk variants to candidate target genes by comprehensively mapping cell-type specific chromatin interactions. We performed a melanoma GWAS re...

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Literature Corpus work
703d02c0-92b4-5eec-8c27-d14a8e998255
DOI
10.1101/2024.11.14.24317204
Open publication

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Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of<i>cis</i>-regulationDOI 10.1101/2024.11.14.24317204
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