Article

The Genetic Architecture of Cutaneous Melanoma Across the Variant Spectrum

2026-06-09

Abstract excerpt

<title>Abstract</title> <p>Cutaneous melanoma is an aggressive skin cancer with a predominant and rising incidence in fair-skinned populations. Here, we systematically characterized its genetic architecture across the allele-frequency spectrum and functional genomic landscape. We identified 126 susceptibility loci through a GWAS meta-analysis of 1,398,034 individuals, including 92 not previously reported. Spatial...

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Literature Corpus work: b245b497-2ac7-5455-8309-ae4f355c5053
DOI: 10.21203/rs.3.rs-9905413/v1

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