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Cathepsin in Alzheimer's Disease, Parkinson's Disease and Dementia with Lewy Bodies: Mendelian Randomization Study

2024-02-28

Abstract excerpt

<h4>Background: </h4> Observational studies indicate a strong association between most neurodegenerative disorders and cathepsin, although the causative link remains unclear. Methods This research utilized Mendelian Randomization (MR) with genetic markers linked to cathepsins as instrumental variables, and analyzed public Genome-Wide Association Studies (GWASs) summary data of individuals with European ancestry f...

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Literature Corpus work
7036ffbe-7e57-59dc-9c7e-2930865de5a2
DOI
10.21203/rs.3.rs-3977553/v1
Open publication

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Cathepsin in Alzheimer's Disease, Parkinson's Disease and Dementia with Lewy Bodies: Mendelian Randomization StudyDOI 10.21203/rs.3.rs-3977553/v1
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