Article
Mendelian Randomization Analysis of Different Cathepsin Isoforms Associated with Neurodegenerative Diseases.
Current neurovascular research - 1 Jan 2026
Yang Fei, Shi XinYu, Wang YiNi, Yin YaPing, Wu HaoYu, Ma Kun
Abstract excerpt
INTRODUCTION: Recent studies indicate that cathepsins play an important role in neurodegenerative diseases. However, further exploration is required to determine the association between each isoform of cathepsin and disease. This study aimed to evaluate the potential causal effects of individual cathepsin isoforms on Alzheimer's Disease (AD), Parkinson's Disease (PD), and epilepsy using Mendelian Randomization...
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