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Article

Cathepsin-mediated regulation of alpha-synuclein in Parkinson’s disease: a Mendelian randomization study

30 May 2024

Abstract excerpt

Objective The observational association between cathepsin and Parkinson’s disease (PD) has been partially explored in previous research. However, the causal relationship remains unclear. In this study, our objective is to investigate the causal link between cathepsin and PD using Mendelian randomization (MR) analysis and elucidate the underlying mechanisms governing their interaction. Methods Utilizing...

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PMID: 38872630
DOI: 10.3389/fnagi.2024.1394807

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