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Article

Cathepsins and cancer risk: a Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Deng Tingting, Lu Xixue, Jia Xuemin, Du Jinxin, Wang Lijuan, Cao Baorui, Yang Meina, Yin Ying, Liu Fanjie

Abstract excerpt

Background: Previous observational epidemiological studies reported an association between cathepsins and cancer, however, a causal relationship is uncertain. This study evaluated the causal relationship between cathepsins and cancer using Mendelian randomization (MR) analysis. Methods: We used publicly available genome-wide association study (GWAS) data for bidirectional MR analysis. Inverse variance weighting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38883596
DOI: 10.3389/fendo.2024.1428433
PMCID: PMC11176415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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