Article

Mesoscale Imaging of Cortical Sensorimotor Integration in Huntington’s Disease Mice During Reward-Guided Behaviour

2025-04-23

Abstract excerpt

Huntington’s disease (HD) is a neurodegenerative disorder that affects numerous brain functions, yet how altered sensory processing contributes to behavioral and learning deficits remains poorly understood. Previous wide-field mesoscale imaging and electrophysiological recording from anesthetized HD mice revealed that sensory stimulation induced exaggerated, prolonged cortical activity across more brain regions co...

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Literature Corpus work: 70073b0a-fc3a-5f7f-b029-806b10ffd83f
DOI: 10.1101/2025.04.23.648272

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