Article

Revealing hidden knowledge in amnestic mice

2025-01-09

Abstract excerpt

Alzheimer’s disease (AD) is a form of dementia in which memory and cognitive decline is thought to arise from underlying neurodegeneration. These cognitive impairments, however, are transient when they first appear and can fluctuate across disease progression. Here, we investigate the neural mechanisms underlying fluctuations of performance in amnestic mice. We trained APP/PS1+ mice on an auditory go/no-go task th...

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Literature Corpus work: d4d42730-8b7f-5f45-b171-65a3b3b143f8
DOI: 10.1101/2025.01.09.632026

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