Article

Generation of a Ym1 Deficient Mouse utilising CRISPR-Cas9 in CB6 Embryos

2025-03-13

Abstract excerpt

Chitinase-like proteins (CLPs) are of wide interest due to their significant roles during both biological and pathological processes. Human CLPs such as YKL-40 have been suggested as biomarkers of disease severity in many conditions. Murine CLPs include Brp39, Ym1, and Ym2 and these are similarly upregulated in multiple mouse models of pathology. Investigation of these molecules, particularly Ym1 and Ym2, is plagu...

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Literature Corpus work: 6fe36ada-1dae-5732-9ff1-d8d96529b127
DOI: 10.1101/2025.03.10.642405

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