Article
Role of mammalian chitinases in asthma.
International archives of allergy and immunology - 1 Jan 2009
Shuhui Lim, Mok Yu-Keung, Wong W S Fred
Abstract excerpt
Asthma is a chronic inflammatory disease characterized by airway inflammation, mucus hypersecretion and airway hyperresponsiveness. Mechanisms underlying the pathogenesis of asthma are not fully understood. In recent years, there are mounting evidences demonstrating that mammalian chitinases may play a key role in mediating the T-helper 2 cell-driven inflammatory response that is commonly associated with asthma....
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