Article

A Virus Genetic System To Analyze the Fusogenicity of Human Cytomegalovirus Glycoprotein B Variants

2023-03-01

Abstract excerpt

Viruses can induce the fusion of infected and neighboring cells, leading to the formation of syncytia. Cell-cell fusion is mediated by viral fusion proteins on the plasma membrane of infected cells that interact with cellular receptors on neighboring cells. Viruses use this mechanism to spread rapidly to adjacent cells or escape host immunity. For some viruses, syncytium formation is a hallmark of infection and a...

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Literature Corpus work: 6fd30f53-2c05-5ef8-b7ad-4b3d98bf1c0f
DOI: 10.20944/preprints202303.0007.v1

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