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Characterization of Human Cytomegalovirus Glycoprotein-Induced Cell-Cell Fusion

26 May 2005

Abstract excerpt

Human cytomegalovirus (CMV) infection is dependent on the functions of structural glycoproteins at multiple stages of the viral life cycle. These proteins mediate the initial attachment and fusion events that occur between the viral envelope and a host cell membrane, as well as virion-independent cell-cell spread of the infection. Here we have utilized a cell-based fusion assay to identify the fusogenic...

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PMID: 15919936
DOI: 10.1128/jvi.79.12.7827-7837.2005

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