Article
Recombinant cytomegaloviruses for study of replication and pathogenesis.
Intervirology - 1 Jan 1996
Mocarski E S, Kemble G W
Abstract excerpt
Systematic mutagenesis of large viral genomes such as those of the cytomegaloviruses requires strategies for identifying relevant functions as well as for detailed analysis of particular genes. A number of genetic markers that have been developed in other biological systems have been useful for insertion mutagenesis in these viruses. Thus far, 57 of the over 227 genes carried by wild-type human cytomegalovirus...
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