Article

Mutational Analysis of Interleukin-11 and its Consequences on Cancer and COVID-19 Related Cytokine Storm -An Extensive Molecular Dynamics Study

2024-01-31

Abstract excerpt

Interleukin-11 is a pleiotropic cytokine that is known to play an important role in the progression of various forms of cancer by modulating the survival and proliferation of tumour cells. IL11 also demonstrates a structural homology to IL6 - the predominant cytokine involved in COVID-19. This makes IL11 a potential therapeutic target in both diseases. This study aimed to evaluate the impact of two mutations- R135...

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Literature Corpus work: 6fa8c70a-dca1-53aa-aeeb-a45197410273
DOI: 10.22541/au.170667144.43048286/v1

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