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Utilising novel Mendelian randomization approaches to investigate a potential causal effect of fetal growth on maternal cardiometabolic risk in the UK Biobank

2025-07-18

Abstract excerpt

Mothers of low birth weight infants are at increased risk of cardiovascular disease in later life. It is hypothesised this reflects a combination of 1) fetal factors influencing maternal vasculature via placental implantation, which also independently affect fetal growth, and 2) confounding by genetics and/or the environment whereby women with a pre-disposed risk of cardiometabolic dysfunction may have an impaired...

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Literature Corpus work
6fa6c3b7-d101-5a5c-9263-13cd04d18293
DOI
10.1101/2025.07.17.25331747
Open publication

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Utilising novel Mendelian randomization approaches to investigate a potential causal effect of fetal growth on maternal cardiometabolic risk in the UK BiobankDOI 10.1101/2025.07.17.25331747
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