Article
Investigating a Potential Causal Relationship Between Maternal Blood Pressure During Pregnancy and Future Offspring Cardiometabolic Health.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 2022
Wang Geng, Bhatta Laxmi, Moen Gunn-Helen, Hwang Liang-Dar, Kemp John P, Bond Tom A, Åsvold Bjørn Olav, Brumpton Ben, Evans David M, Warrington Nicole M
Abstract excerpt
Observational epidemiological studies have reported that higher maternal blood pressure (BP) during pregnancy is associated with increased future risk of offspring cardiometabolic disease. However, it is unclear whether this association represents a causal relationship through intrauterine mechanisms. We used a Mendelian randomization (MR) framework to examine the relationship between unweighted maternal genetic...
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