Article
Disentangling the link between maternal influences on birth weight and disease risk in 36,211 genotyped mother-child pairs.
Communications biology - 12 Feb 2024
Leinonen Jaakko T, Pirinen Matti, Tukiainen Taru
Abstract excerpt
Epidemiological studies have robustly linked lower birth weight to later-life disease risks. These observations may reflect the adverse impact of intrauterine growth restriction on a child's health. However, causal evidence supporting such a mechanism in humans is largely lacking. Using Mendelian Randomization and 36,211 genotyped mother-child pairs from the FinnGen study, we assessed the relationship between...
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