Article

Glucocorticoid-regulated bidirectional enhancer RNA transcription pinpoints functional genetic variants linked to asthma

2022-11-13

Abstract excerpt

Genome-wide association studies of asthma have not explained environmental risk or variable clinical efficacy of glucocorticoids. Bidirectional enhancer RNA (eRNA) transcription is a widespread response to environmental signals and glucocorticoids. Therefore, we investigated whether single nucleotide polymorphisms (SNPs) within dynamically regulated eRNA-transcribing regions contribute to genetic variation in asth...

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Literature Corpus work: 6f91acad-1eaf-5e61-bee4-2e73db79bb33
DOI: 10.1101/2022.11.10.22281906

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