Article
Epigenome-wide association study of asthma and wheeze in childhood and adolescence
2017-05-09
Abstract excerpt
Asthma heritability has only been partially explained by genetic variants and is known to be sensitive to environmental factors, implicating epigenetic modifications such as DNA methylation in its pathogenesis. Using data collected in the Avon Longitudinal Study of Parents and Children (ALSPAC), we assessed associations of asthma and wheeze with DNA methylation at 7.5 years and 16.5 years, at over 450,000 CpG site...
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Identifiers and source
- Literature Corpus work
- 6b6cd352-b947-5906-ba1c-89a693c5f8df
- DOI
- 10.1101/135301