Article
Decoding the genetic and epigenetic basis of asthma.
Allergy - 1 Apr 2023
Stikker Bernard S, Hendriks Rudi W, Stadhouders Ralph
Abstract excerpt
Asthma is a complex and heterogeneous chronic inflammatory disease of the airways. Alongside environmental factors, asthma susceptibility is strongly influenced by genetics. Given its high prevalence and our incomplete understanding of the mechanisms underlying disease susceptibility, asthma is frequently studied in genome-wide association studies (GWAS), which have identified thousands of genetic variants...
Topics
- Humans
- Genome-Wide Association Study
- Epigenesis, Genetic
- Epigenomics
- Asthma
- Genomics
- Genetic Predisposition to Disease
