Article
Epigenome-wide association study of asthma and wheeze in childhood and adolescence.
Clinical epigenetics - 1 Jan 2017
Arathimos Ryan, Suderman Matthew, Sharp Gemma C, Burrows Kimberley, Granell Raquel, Tilling Kate, Gaunt Tom R, Henderson John, Ring Susan, Richmond Rebecca C, Relton Caroline L
Abstract excerpt
BACKGROUND: Asthma heritability has only been partially explained by genetic variants and is known to be sensitive to environmental factors, implicating epigenetic modifications such as DNA methylation in its pathogenesis. METHODS: Using data collected in the Avon Longitudinal Study of Parents and Children (ALSPAC), we assessed associations of asthma and wheeze with DNA methylation at 7.5 and 16.5 years, at over...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.