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Influence of basal media composition on barrier fidelity within human pluripotent stem cell-derived blood-brain barrier models

2021-03-01

Abstract excerpt

It is increasingly recognized that brain microvascular endothelial cells (BMECs), the principle component of the blood-brain barrier (BBB), are highly sensitive to soluble cues from both the bloodstream and the brain. This concept extends in vitro , where the extracellular milieu can also influence BBB properties in cultured cells. However, the extent to which baseline culture conditions can affect BBB properties...

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Literature Corpus work
6f7636d8-644b-581d-8284-4d1ba466fc53
DOI
10.1101/2021.03.01.433282
Open publication

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Influence of basal media composition on barrier fidelity within human pluripotent stem cell-derived blood-brain barrier modelsDOI 10.1101/2021.03.01.433282
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