Article

Highly multiplexed quantifications of 299 somatic mutations in colorectal cancer patients by automated MALDI-TOF mass spectrometry

2020-09-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Detection of somatic mutations in tumor tissues helps to understand tumor biology and guide treatment selection. Methods such as quantitative PCR can analyze a few mutations with high efficiency, while next generation sequencing (NGS) based methods can analyze hundreds to thousands of mutations. However, there is a lack of cost-effective method for quantitativel...

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Literature Corpus work: 6f58853d-2ad0-5d60-a216-49854430edd9
DOI: 10.21203/rs.2.12726/v4

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