Article
A multiplex technology platform for the rapid analysis of clinically actionable genetic alterations and validation for BRAF p.V600E detection in 1549 cytologic and histologic specimens.
Archives of pathology & laboratory medicine - 1 Mar 2014
Smith David L, Lamy Aude, Beaudenon-Huibregtse Sylvie, Sesboüé Richard, Laosinchai-Wolf Walairat, Sabourin Jean-Christophe, Labourier Emmanuel
Abstract excerpt
CONTEXT: Current clinicopathologic assessment of malignant neoplastic diseases entails the analysis of specific genetic alterations that provide diagnostic, prognostic, or therapy-determining information. OBJECTIVE: To develop and validate a robust molecular method to detect clinically relevant mutations in various tissue types and anatomic pathology specimens. DESIGN: Genes of interest were amplified by...
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