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Article

A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.

BMC cancer - 16 Mar 2010

Fumagalli Debora, Gavin Patrick G, Taniyama Yusuke, Kim Seung-Il, Choi Hyun-Joo, Paik Soonmyung, Pogue-Geile Katherine L

Abstract excerpt

BACKGROUND: An increasing number of studies show that genetic markers can aid in refining prognostic information and predicting the benefit from systemic therapy. Our goal was to develop a high throughput, cost-effective and simple methodology for the detection of clinically relevant hot spot mutations in colon cancer. METHODS: The Maldi-Tof mass spectrometry platform and OncoCarta panel from Sequenom were used...

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Share to Class I Phosphatidylinositol 3-Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20233444
DOI: 10.1186/1471-2407-10-101
PMCID: PMC2845115

Genes

BRAF
KRAS
ABL1
AKT1
MET
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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