Article
Multiplex mutation screening by mass spectrometry in gastrointestinal stromal tumours.
Pathology - 1 Aug 2012
Kang Guhyun, Lee Jeeyun, Jang Ki Taek, Beadling Carol, Corless Chistopher L, Heinrich Micheal C, Park Joon Oh, Kang Won Ki, Park Cheol Keun, Kim Kyoung-Mee
Abstract excerpt
AIMS: Clinical decision making and optimal clinical trial design based on cancer genetic information will be increasingly informed by the mutational status of multiple genes. METHODS: We performed mutation screening on 22 fresh frozen gastrointestinal stromal tumours (GISTs) using a multiplexed oncogene screening panel with a mass spectroscopy readout (MassARRAY). The panel can detect 390 known mutations across...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.